Purpose

Dexamethasone is an evidence-based treatment of acute migraine. This is a randomized comparison of two different doses of dexamethasone for acute migraine. All patients will also be treated with metoclopramide.

Condition

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Moderate or severe migraine

Exclusion Criteria

  • Medication contra-indication
  • Concern for secondary cause of headache

Study Design

Phase
Phase 4
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
Dexamethasone 4mg
Dexamethasone 4mg, administered intravenously
  • Drug: Dexamethasone 4mg
    Dexamethasone 4mg + metoclopramide 10mg, intravenously
Active Comparator
Dexamethasone 16mg
Dexamethasone 16mg, administered intravenously
  • Drug: Dexamethasone 16mg
    Dexamethasone 16mg + metoclopramide 10mg, intravenously

Recruiting Locations

Montefiore Medical Center
Bronx, New York 10467
Contact:
Benjamin Friedman, MD
718-920-6626
befriedm@montefiore.org

More Details

NCT ID
NCT04112823
Status
Recruiting
Sponsor
Montefiore Medical Center

Study Contact

Eddie Irizarry, MD
718-920-6626
eddiriza@montefiore.org

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.